Orthopedic Histopathology Service Center

Our team of highly skilled technicians and researchers, along with our state of the art facility, are dedicated to providing exceptional GLP-like histopathology services for all orthopedic specialties as well as routine scientific research laboratories.

The Orthopedic Histopathology Service Center (OHSC) is able to provide quick estimates for grant proposal purposes as well as live quotes for awarded projects along with final invoicing and billing.  To request an estimate for grant submission, please complete the OHSC Project Estimate Form.

Once your project is funded and you have end on In life dates, you can request full service for your project.  You may request a consultation by checking the appropriate box on the request form or by phone or email.  If you request a consultation on the from, we will schedule a time to call you and review your project needs in detail.  To request service and a final quote, please complete the OHSC Service Request Form.

Complete the Chain of Custody form prior to delivery of any samples to the OHSC Laboratory.  This must be printed and the original copy brought with the samples to the lab.  We suggest samples be brought to the lab within 24 hours of sacrifice to ensure proper fixation and handling.  Complete a new form for each group for projects with multiple end dates. 

Upon project completion,you will be notified via email and will be able to pick up all  raw data for your project including tissue blocks, slides and paperwork.  All projects placed at the OHSC are carried out in accordance with GLP guidelines and all raw data is available for every project.

OHSC Project Estimate

OHSC Service Request Form

OHSC Study Chain of Custody Form

Contact Information

2501 Crosspark Road
Suite B, Room 126
Coralville, Iowa 52241
Phone: 319-353-1800
Email: ortho-ohsc@uiowa.edu

Routine Histology

Our paraffin laboratory produces routine histology slides from formalin fixed paraffin embedded tissue samples.  The lab is furnished with state-of-the-art equipment, including high throughput automated tissue processing and staining instruments, specialized automated microtomes for sectioning boney tissues as well as radiographic and digital imaging systems.  

Special Services

Our plastic laboratory specializes in processing of nerve tissue and calcified bone, with and without implants, into plastic epoxy and acrylic resins.  This lab is furnished with multiple Exakt grinding systems and cutting-edge plastic microtomy equipment, including a brand new Rowiak TissueSurgeon laser microtome.  These systems are engineered for novel, large scale applications.  Our knowledge and expertise allow for protocol development of staining specifically for plastic embedded tissues.

Immunohistochemistry

The OHSC laboratory is skilled in the preparation,   detection and visualization of antibody labeling in tissue.  This service includes standard IHC on paraffin or plastic preparations which have been developed and validated for use in many different species. We are also able to develop custom protocols upon request and can offer multiplex staining of up to 4 different antibody labels using revolutionary, automated IHC staining platforms.